Altered Functional Connectivity of the Basal Nucleus of Meynert in Subjective Cognitive Impairment, Early Mild Cognitive Impairment, and Late Mild Cognitive Impairment
نویسندگان
چکیده
منابع مشابه
Identification of mild cognitive impairment disease using brain functional connectivity and graph analysis in fMRI data
Background: Early diagnosis of patients in the early stages of Alzheimer's, known as mild cognitive impairment, is of great importance in the treatment of this disease. If a patient can be diagnosed at this stage, it is possible to treat or delay Alzheimer's disease. Resting-state functional magnetic resonance imaging (fMRI) is very common in the process of diagnosing Alzheimer's disease. In th...
متن کاملAltered Functional Connectivity of the Basal Nucleus of Meynert in Mild Cognitive Impairment: A Resting-State fMRI Study
Background: Cholinergic dysfunction plays an important role in mild cognitive impairment (MCI). The basal nucleus of Meynert (BNM) provides the main source of cortical cholinergic innervation. Previous studies have characterized structural changes of the cholinergic basal forebrain in individuals at risk of developing Alzheimer's disease (AD). However, whether and how functional connectivity of...
متن کاملFunctional Connectivity Disruption in Subjective Cognitive Decline and Mild Cognitive Impairment: A Common Pattern of Alterations
Functional connectivity (FC) alterations represent a key feature in Alzheimer's Disease (AD) and provide a useful tool to characterize and predict the course of the disease. Those alterations have been also described in Mild Cognitive Impairment (MCI), a prodromal stage of AD. There is a growing interest in detecting AD pathology in the brain in the very early stages of the disorder. Subjective...
متن کاملEffect of Aerobic Exercise on HbA1c and Cognitive Function in Prediabetes Patients with Mild Cognitive Impairment
Objective: This study aimed to investigate the effects of moderate to high-intensity aerobic exercise on HbA1c (Glycated hemoglobin), FBS (fasting blood sugar) and cognitive function in mild cognitive impairment prediabetes patients. Materials and Methods: Seventeen elderly mild cognitive impairment (age 55-70) men and women were selected and were randomly divided into 2 groups as aerobic (n=1...
متن کاملProfile of Cognitive Complaints in Vascular Mild Cognitive Impairment and Mild Cognitive Impairment
Objective. Vascular mild cognitive impairment (VaMCI) is differentiated from mild cognitive impairment (MCI) by the presence of vascular events such as stroke or small vessel disease. Typically, MCI and VaMCI patients present with subjective complaints regarding cognition; however, little is known about the specific nature of these complaints. We aimed to create a profile of subjective cognitiv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2021
ISSN: 1663-4365
DOI: 10.3389/fnagi.2021.671351